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PromethION Flow Cell Packs and Ligation Sequencing Kits

Waiver type - Procurement: Nonavailability

Agency: NATIONAL INSTITUTES OF HEALTH (7529) • Product Service Code (PSC) : 6640 | Last Modified: 08/08/2024

Procurement Summary

The purpose of this acquisition is to purchase the PromethIONion Flow cells (or equal). Nanopore PromethION flow cells, developed by Oxford Nanopore Technologies, represent a groundbreaking advancement in the field of genomics. Nanopore sequencing technology enables the direct, real-time analysis of long DNA and RNA molecules as they pass through nanopores. This method offers significant advantages over traditional short-read sequencing technologies, including the ability to generate ultra-long reads, high throughput, and real-time data acquisition. PromethION, one of the most powerful platforms within the nanopore sequencing family, is designed for large-scale, high-throughput applications, making it ideal for comprehensive genomic studies.

Waiver Rationale Summary

The Laboratory of Genetics and Genomics (LGG)/Functional Epigenetics Unit (FEU) requires PromethION Flow Cell (R10.4.1) sequencing kits to be used with Nanopore sequencing technology, which has been in use for several years now and has become optimized for use in in-house sequencing. A Flow Cell (R10.4.1) is a consumable used with the PromethION MinION and GridION devices. It contains the proprietary sensor array, Application -Specific Integrated Circuit (ASIC) and R10.4.1 nanopores suitable for all ID experiments. This technology can offer direct sequencing of native DNA and RNA as well as amplified samples. The sequencing happens in real time. Once the flow cells have been purchased, samples can easily be run in flow cells. These flow cells have the advantage of reading any length nucleic acid and can be used until the nanopores have reached their life expectancy. New flow cells must therefore be purchased as the used ones become inadequate over time.

Did / Will the solicitation include one of the standard BAA provisions announcing the agency’s intention to provide a price preference for domestic end products and construction material?

Yes

Was a sources sought or Request for Information issued?

Yes

OMB Determination

Consistent with Policy

Product

LABORATORY EQUIPMENT AND SUPPLIES

NAICS

334516 - Analytical Laboratory Instrument Manufacturing

Date Submitted

07/24/2024

Procurement Instrument Identifier (PIID)

Solicitation ID

N/A

Procurement Stage

Pre-solicitation

Expected Maximum Duration of the Proposed Waiver

Instant Delivery Only

Waiver Coverage

Individual Waiver

Funding Agency

NATIONAL INSTITUTES OF HEALTH